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Phys Med Rehabil Clin N Am · Nov 2016
ReviewDextrose Prolotherapy: A Narrative Review of Basic Science, Clinical Research, and Best Treatment Recommendations.
- Kenneth Dean Reeves, Regina W S Sit, and David P Rabago.
- Private Practice, 4740 El Monte Roeland Park, KS 66205, USA; Department of Physical Medicine and Rehabilitation, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA. Electronic address: DeanReevesMD@gmail.com.
- Phys Med Rehabil Clin N Am. 2016 Nov 1; 27 (4): 783-823.
AbstractProlotherapy involves the injection of nonbiologic solutions, typically at soft tissue attachments and within joint spaces, to reduce pain and improve function in painful musculoskeletal conditions. A variety of solutions have been used; dextrose prolotherapy is the most rigorously studied and is the focus of this review. Although the mechanism of action is not clearly known, it is likely to be multifactorial. Data on effectiveness for temporomandibular dysfunction are promising but insufficient for recommendations. Research on the mechanism of action and clinical effects of dextrose prolotherapy are under way.Copyright © 2016 Elsevier Inc. All rights reserved.
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