• M Zampolini, F Corea, R Avesani, P Boldrini, A De Tanti, M G Di Stefano, R Formisano, G Lamberti, F Lombardi, A Mazzucchi, C Pistarini, M Taricco, and A Citterio.
• Operative Unit of Severe Acquired Brain Lesions, Asl 3 Umbria, Foligno, Perugia, Italy - m.zampolini@asl3.umbria.it.
• Eur J Phys Rehabil Med. 2013 Jun 1; 49 (3): 365-72.

BackgroundThe rehabilitation of the persons with Severe Acquired Brain Injury (ABI) is an important concern to be approached with a comprehensive program aimed to improve the recovery of patients.The efficacy of an early and intensive rehabilitation program has been shown in large number of studies. Few studies focused on the prevalence of TBI and the data are often extrapolated in indirect ways.AimAn analysis of the demographic characteristics of the population included in the GISCAR (Gruppo Italiano per lo Studio delle Gravi Cerebrolesioni Acquisite e Riabilitazione- Italian Group for the Study of the severe ABI) database, type and conditions associated to the index event; the treatment administered during hospitalization; and the prognosis according to outcome measures.DesignThe study was an observational prospective survey looking at management of ABI (both traumatic and non-traumatic).SettingIn hospital rehabilitation.PopulationPatients consecutively admitted in each of the 52 GISCAR centres.MethodsEvery centre included a consecutive cohort and recorded demographic data and index event characteristics.ResultsIn the study population were included 2626 subjects suffering of a severe ABI. The difference of length of stay (LOS) was significantly different with 67.5 days for traumatic patients compared to the 80 days of non traumatic ones. In the study population the probability of discharge at home is significantly greater for the traumatic condition (odds ratio 0,4587; CI 0.3671-0.5731). The overall benefit of the rehabilitative treatment was encountered in a net gain in all disability scores taken into account: LCF classes; DRS as well as GOS scores. At discharge the main destination for severe ABI patients was home (67.2%).ConclusionsA large number of patients admitted in Italian rehabilitative facilities for a severe ABI suffered from a TBI, more often these subjects were young male victims of road accident. The majority of subjects during the rehabilitative hospitalization demonstrated a significant recovery.Clinical Rehabilitation ImpactConsidering the evidence of an early treatment benefit the delay ofthe rehabilitation program start is far from being satisfactory. The high frequency of the home discharge indicate a good compliance of national family network.

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