• J Stroke Cerebrovasc Dis · Aug 2020

    Case Reports

    Dabigatran-induced chronic progressive immune hemolytic anemia: A case report.

    • Jin-Hong Gong, Guang-Jun Liu, Feng Zhou, and Zhi-Qiang Sun.
    • Department of Pharmacy, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Xinglong Road 29, Tianning District, Changzhou 213000, China; Department of Pharmaceutics, Department of Hematology, College of Pharmaceutical Sciences, Soochow University, Suzhou, China.
    • J Stroke Cerebrovasc Dis. 2020 Aug 1; 29 (8): 104924.

    AbstractDabigatran is an orally active direct thrombin inhibitor, initially approved by FDA for the prophylaxis of stroke and systemic embolism in the setting of non-valvular atrial fibrillation (NVAF). Major bleeding is its most common adverse event which is of great concern. However, other types of adverse events such as esophagitis, esophageal ulcer, exanthem and pustular eruptions were reported increasingly in recent years. We present a case of immune hemolytic anemia (IHA) due to dabigatran use in a 72-year-old male with NVAF. This new and rare reported type of adverse event associated with dabigatran suggests that dabigatran may be a new cause of drug-induced immune hemolytic anemia (DIIHI).Copyright © 2020. Published by Elsevier Inc.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…