• Rheumatol. Int. · Dec 2018

    Review Case Reports

    Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review.

    • Rada Miskovic, Aleksandra Plavsic, Jasna Bolpacic, Sanvila Raskovic, Jovan Ranin, and Mirjana Bogic.
    • Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia. rada_delic@hotmail.com.
    • Rheumatol. Int. 2018 Dec 1; 38 (12): 2315-2321.

    AbstractA possible association between strongyloidiasis and systemic vasculitis is rarely reported in the literature. We report the case of a patient with severe strongyloidiasis and an angiographic finding consistent with polyarteritis nodosa. Diagnosis of strongyloidiasis was made by finding of larvae and adult parasites in samples of the upper gastrointestinal tract mucosa and stool. The patient was treated with albendazole, ivermectin and corticosteroid withdrawal. This therapy led to the resolution of symptoms, with repeated stool samples negative for S. stercoralis. However, the clinical course was complicated with pulmonary tuberculosis. Despite tuberculostatic therapy and supportive measures, a lethal outcome occurred. The report is followed by a focused review of the available literature on the association of strongyloidiasis and systemic vasculitis.

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