• İlknur Öztürk Ünsal, Sema Hepşen, Pınar Akhanlı, Murat Çalapkulu, Muhammed Erkam Sencar, Ali Yalçındağ, and Erman Çakal.
• Department of Endocrinology and Metabolism, Dışkapı Yıldırım Beyazıt Training and Research Hospital, University of Health Sciences, Ankara, Turkey
• Turk J Med Sci. 2021 Apr 30; 51 (2): 716-721.

Background/AimAutoimmune thyroid disease in women is associated with subfertility and early pregnancy loss, and patients with primary ovarian insufficiency have a high prevalence of thyroid autoimmune disorders. The aim of this study was to investigate the association between Hashimoto thyroiditis (HT) and ovarian reserve.Materials And MethodsLevels of serum thyroid stimulating hormones, thyroid autoantibodies, and anti-Müllerian hormone (AMH) were measured in women with HT and a healthy control group between 2018 and 2019.ResultsEvaluation was made of 108 premenopausal women with HT, and a control group of 172 healthy females with normal antithyroid antibody levels and thyroid function. Serum AMH levels were determined to be significantly lower in the HT group compared to the control group.ConclusionOvarian reserve evaluated by serum AMH concentration is affected by thyroid autoimmunity independently of antithyroid antibodies type or titers.This work is licensed under a Creative Commons Attribution 4.0 International License.

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