• Br J Anaesth · Nov 1992

    Is the "K-type" caffeine-halothane responder susceptible to malignant hyperthermia?

    • F R Ellis, P J Halsall, and P M Hopkins.
    • Leeds Malignant Hyperthermia Investigation Unit, St James's University Hospital, Leeds.
    • Br J Anaesth. 1992 Nov 1; 69 (5): 468-70.

    AbstractThe "K-type" designation is used to describe a patient being investigated for malignant hyperthermia (MH) when concurrent administration of caffeine and halothane induces muscle contracture (rigidity, spasm) in vitro, but when halothane and caffeine given separately produce a normal response. It is accepted in some centres that K-type individuals are susceptible to malignant hyperthermia (MHS). In this paper, the K-type is shown not to correlate with the MH susceptible (MHS) status as accepted by the European MH group.

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