• J Craniofac Surg · Mar 2013

    Case Reports

    Rhino-orbito-cerebral mucormycosis in patients with diabetic ketoacidosis.

    • Ramazan Gen, Elif Şahin Horasan, Yusuf Vaysoğlu, Rabia Bozdoğan Arpaci, Gülden Ersöz, and Cengiz Özcan.
    • Department of Endocrinology and Metabolism, Mersin University Medical School, Mersin, Turkey.
    • J Craniofac Surg. 2013 Mar 1; 24 (2): e144-7.

    AbstractMucormycosis is a life-threatening fungal infection that occurs in immunocompromised patients. The most common predisposing risk factor for mucormycosis is diabetes mellitus. Rhino-orbito-cerebral mucormycosis is the most common form in diabetic patients and is characterized by paranasal sinusitis, ophthalmoplegia with blindness, and unilateral proptosis with cellulitis, facial pain with swelling, headache, fever, rhinitis, granular or purulent nasal discharge, nasal ulceration, epistaxis, hemiplegia or stroke, and decreased mental function. Diabetic ketoacidosis is the most common and serious acute complication of diabetic patients. We herein report 2 cases of fatal rhino-orbito-cerebral mucormycosis in a patient with diabetic ketoacidosis.

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