• Yaser M K Baghdadi, A Noelle Larson, Mark B Dekutoski, Quanqi Cui, Arjun S Sebastian, Bryan M Armitage, and Ahmad Nassr.
• *Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN †Center of Orthopedic Research and Education (CORE) Institute, Sun City West, AZ ‡Department of Orthopedic Surgery, Guang An Men Hospital, Beijing, China; and §Department of Orthopedic Surgery, University of Hawaii, Honolulu, Hawaii.
• Spine. 2014 Feb 1; 39 (3): E166-73.

Study DesignRetrospective matched-cohort analysis.ObjectiveTo evaluate the change in radiographical parameters in patients undergoing interbody fusion and posterior instrumentation compared with posterior spine fusion (PSF) alone for degenerative scoliosis.Summary Of Background DataLittle is known about the effect of lateral interbody fusion (LIF) on sagittal plane correction in the setting of degenerative scoliosis. We performed a retrospective study to investigate these changes compared with PSF.MethodsBetween 1997 and 2011, 33 patients had LIF at 181 levels between T8 and L5 vertebrae for the treatment of degenerative scoliosis (mean; 5 ± 2 levels). Of those, 23 patients had additional anterior lumbar interbody fusion (ALIF) at 37 levels between L4 and S1 vertebrae (mean; 1.6 ± 0.5 levels). A 1:1 matched control of patients who underwent PSF was performed. Patients were matched by age, sex, and diagnosis. Clinical and radiographical data were collected and compared between the matched cohorts.ResultsLumbar lordosis (LL) was significantly restored in the LIF ± ALIF compared with PSF cohort (44° ± 14° vs. 36° ± 15°, P = 0.02). The segmental LL over the 102 LIF levels significantly improved from 12°± 10° to 21°± 13° postoperatively (P < 0.0001). However, the change over the 37 ALIF levels was not significant (from 30° ± 15° to 29° ± 9°, P = 0.8). Sagittal plane alignment was improved in the LIF ± ALIF compared with PSF cohort and trended toward but did not reach significance (3.8 ± 3.2 cm vs. 6.2 ± 5.7 cm, P = 0.09). Sacral slope was significantly higher in the LIF ± ALIF compared with PSF cohort (33° ± 11° vs. 28° ± 10°, P = 0.03). Pelvic tilt was lower in the LIF ± ALIF compared with PSF cohort and trended toward but did not reach significance (22° ± 10° vs. 26° ± 10°, P = 0.08).ConclusionLL and sacral slope had mildly but statistically improved in the interbody fusion cohort compared with PSF cohort. Sagittal alignment and pelvic tilt trended toward but did not reach statistical significance. Segmental LL was improved at LIF levels more than at ALIF levels.Level Of Evidence3.

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