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- Eung Ju Kim, Sungeun Kim, Hong Seog Seo, Yong Jik Lee, Jae Seon Eo, Jae Min Jeong, Boeun Lee, Jae Young Kim, Young Mi Park, and Myeongsook Jeong.
- Cardiovascular Center, Korea University Guro Hospital, Korea University College of Medicine, Seoul, South Korea.
- J. Nucl. Med. 2016 Nov 1; 57 (11): 1792-1797.
AbstractActivated macrophages take up 18F-FDG via glucose transporters, so this compound is useful for atherosclerosis imaging by PET. However, 18F-FDG application is limited for imaging of the heart and brain, in which glucose uptake is high, and in patients with aberrant glucose metabolism. The aims of this study were to confirm that mannosylated human serum albumin (MSA) specifically binds to the mannose receptor (MR) on macrophages and to test the feasibility of 68Ga-labeled NOTA-MSA for PET imaging of atherosclerotic plaques.© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.
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