• Rev. Med. Virol. · Mar 2021

    Review

    Sex-based differences in severity and mortality in COVID-19.

    • Mustafa Alwani, Aksam Yassin, Raed M Al-Zoubi, Omar M Aboumarzouk, Joanne Nettleship, Daniel Kelly, Ahmad R Al-Qudimat, and Ridwan Shabsigh.
    • Surgical Research Section, Hamad Medical Corporation, Doha, Qatar.
    • Rev. Med. Virol. 2021 Mar 1.

    AbstractThe current coronavirus disease (COVID-19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS-CoV and MERS-CoV, and viral infections in general. Here, we discuss the sex-disaggregated epidemiological data for COVID-19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.© 2021 The Authors. Reviews in Medical Virology published by John Wiley & Sons Ltd.

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