• Hiroko Shojaku, Ryota Hori, Toru Yoshida, Kazuhiro Matsui, Katsuo Shimada, Nobutatsu Takayanagi, and Kyo Noguchi.
• Department of Radiology, University of Toyama.
• Medicine (Baltimore). 2021 Mar 12; 100 (10): e24023e24023.

RationaleFibroadenoma (FA) is a common type of benign breast tumors but ductal carcinoma in situ (DCIS) rarely arises within this tumor type.Patient ConcernsThis case report presents a non-symptomatic 61-year-old woman with FA that was coincidentally found during a breast cancer screening program performed 5 years ago by her city of residence. She had subsequently been followed-up with mammography and breast ultrasound (US). US showed a slightly enlarged tumor and dynamic magnetic resonance imaging (MRI) indicated malignancy within the FA.DiagnosisThe pathological examination revealed low-grade DCIS within the FA.InterventionsThe patient underwent a core needle biopsy followed by breast-conserving therapy with sentinel lymph node biopsy and then postoperative radiation therapy.OutcomesCurrently, she has been followed-up for 2 years without no signs of recurrence.LessonsCareful observation with US followed by dynamic MRI is essential in the early diagnosis of DCIS originating in a FA.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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