• Shin-Ichi Yamada, Kazuyuki Koike, Emiko Tanaka Isomura, Daichi Chikazu, Kenji Yamagata, Masahiro Iikubo, Satoshi Hino, Hideharu Hibi, Kouji Katsura, Seiji Nakamura, Takeshi Nomura, Yoshiyuki Mori, Itaru Tojyo, Narisato Kanamura, Iku Yamamori, Keiko Aota, Shigeyuki Fujita, Hideki Tanzawa, Hiroshi Kurita, and Japanese Stomatological Society.
• Department of Dentistry and Oral Surgery, Shinshu University School of Medicine. Matsumoto.
• Medicine (Baltimore). 2021 Mar 12; 100 (10): e25119e25119.

AbstractThe purpose of the present study was to investigate the efficacy of perioperative oral managements (POMs) on perioperative nutritional conditions in patients undergoing surgery with general anesthesia. Medical records were retrospectively reviewed and the effects of POMs were investigated based on a large number of cases using a multicenter analysis. The profile of serum albumin levels was assessed and compared between patients with and without POMs using the multivariate analysis. Seventeen Eleven thousand and one hundred sixty patients (4,873 males and 6,287 females) were reviewed. Of these, 2710 patients (24.3%) had undergone POMs. The results of a multivariate analysis revealed the significant positive effect of POMs on perioperative serum albumin level (change between at admission and discharge, (Estimate: 0.022, standard error: 0.012, P < .0001). Patient gender, age, surgical site, performance status, the American Society of Anesthesiologists (ASA) physical status classification, operation time, amount of blood loss, and serum albumin level at admission were also significant predictors. Adjusted multivariate analysis of the effects of POMs on perioperative change of serum albumin level in all subjects reveled the significance of POMs intervention (estimate: 0.022, standard error: 0.012, P < .0001). These results suggest that POMs exerts significant positive effects on perioperative serum albumin levels in patients underwent surgery under general anesthesia.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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