• Junhua Shi, Junli Shi, and Shengbo Yang.
• Department of Radiology, Affiliated Hospital of Zunyi Medical University.
• Medicine (Baltimore). 2021 Mar 19; 100 (11): e24977e24977.

IntroductionBreast tubular carcinoma (TC) is a well-differentiated infiltrating ductal carcinoma, common in postmenopausal women.Patient ConcernsTwo patients concerned their abnormality of their breasts, one at deep parasternal higher chest wall in a 74-year-old female and the other behind the nipple in a 39- year-old female.DiagnosisThese masses were detected by mammography, ultrasound and magnetic resonance imaging (MRI) examinations. The parasternal mass identified by mammography showed long spicules along the edges of the mass. Ultrasound examination revealed that these masses had solid irregular hypoechoic nodules. The color Doppler ultrasound of the retro-nipple mass presented with increased blood flow resistance index. The dynamic contrast-enhanced MRI examination of the retro-nipple nodule demonstrated an intensely enhancing mass with a plateau-type time-signal intensity curve.InterventionsTwo cases were surgically removed by local resection of foci under ultrasound guidance.OutcomesThese imaging examinations strongly suggest possible breast tubular carcinoma, which was confirmed by the pathological evaluation of frozen sections from surgically removed masses.ConclusionAlthough uncommon, breast tubular carcinoma may be considered in the differential diagnosis of small solid masses with long spicules at parasternal breast or behind the nipples in adult women.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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