• Biomed Res Int · Jan 2020

    Review

    Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019.

    • Lin Li, Qi Zhou, and Jiancheng Xu.
    • Department of Laboratory Medicine, First Hospital of Jilin University, Changchun 130021, China.
    • Biomed Res Int. 2020 Jan 1; 2020: 7413673.

    AbstractSome patients with coronavirus disease 2019 (COVID-19) show abnormal changes in laboratory myocardial injury markers, suggesting that patients with myocardial injury have a higher mortality rate than those without myocardial injury. This article reviews the possible mechanism of myocardial injury in patients with COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the patients with COVID-19 in aspects of direct infection of myocardial injury, specific binding to functional receptors on cardiomyocytes, and immune-mediated myocardial injury. During hospitalization, the monitoring of laboratory myocardial injury markers in patients of COVID-19 should be strengthened.Copyright © 2020 Lin Li et al.

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