• Ned Tijdschr Geneeskd · Jun 1996

    Case Reports

    [Fatal arrhythmia following administration of suxamethonium in a postpartum woman subsequently found to have dystrophia myotonica].

    • F W Rozendaal and J Rupreht.
    • Academisch Ziekenhuis Rotterdam-Dijkzigt, afd. Anesthesiologie.
    • Ned Tijdschr Geneeskd. 1996 Jun 22; 140 (25): 1317-9.

    AbstractA 28-year-old woman died of irreversible ventricular fibrillation after administration of succinylcholine because of post partum curettage. Afterwards it became known she had undiagnosed myotonic dystrophy. She also had metabolic acidosis because of haemorrhagic hypovolaemia resulting in a probably elevated serum K+ concentration preoperatively. Succinylcholine given to patients with myotonic dystrophy may lead to life threatening hyperkalaemia and cardiac arrest. Therapy should be aimed at immediate lowering of serum K+ concentration with calcium, sodium bicarbonate and hyperventilation.

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