• Expert Rev Anticancer Ther · Jul 2016

    Review Comparative Study

    Stereotactic radiosurgery for intracranial metastases: linac-based and gamma-dedicated unit approach.

    • Filippo Alongi, Alba Fiorentino, Pietro Mancosu, Pierina Navarria, Giaj Levra Niccolò N a Radiation Oncology Department , Sacro Cuore Hospital , Negrar , Italy., Rosario Mazzola, and Marta Scorsetti.
    • a Radiation Oncology Department , Sacro Cuore Hospital , Negrar , Italy.
    • Expert Rev Anticancer Ther. 2016 Jul 1; 16 (7): 731-40.

    IntroductionFor intracranial metastases, the role of stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy is well recognized.Areas CoveredHistorically, the first technology, for stereotactic device able to irradiate a brain tumor volume, was Gamma Knife® (GK). Due to the technological advancement of linear accelerator (Linac), there was a continuous increasing interest in SRS Linac-based applications. In those decades, it was assumed a superiority of GK compared to SRS Linac-based for brain tumor in terms of dose conformity and rapid fall-off dose close to the target. Expert commentary: Recently, due to the Linac technologic advancement, the choice of SRS GK-based is not necessarily so exclusive. The current review discussed in details the technical and clinical aspects comparing the two approaches for brain metastases.

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