• Tech Coloproctol · Jun 2019

    Multicenter Study

    Sacral neuromodulation for fecal incontinence in Latin America: initial results of a multicenter study.

    • L Oliveira, G Hagerman, M L Torres, C M Lumi, J A C Siachoque, J C Reyes, J Perez-Aguirre, J C Sanchez-Robles, V H Guerrero-Guerrero, S M Regadas, V G Filho, G Rosato, E Vieira, L Marzan, D Lima, E Londoño-Schimmer, and S D Wexner.
    • Department of Anorectal Physiology of Rio de Janeiro, CEPEMED, Rua Visc.de Pirajá 414/812, Ipanema, Rio de Janeiro, 22410-002, Brazil. draluciaol@gmail.com.
    • Tech Coloproctol. 2019 Jun 1; 23 (6): 545-550.

    BackgroundSacral neuromodulation (SNM) is a widely used therapeutic option for fecal incontinence (FI). Larger series are mainly from Western countries, while few reports address the results of SNM in less developed or less wealthy countries. The aim of the present study was to evaluate the efficacy of SNM in patients with FI in Latin America.MethodsA retrospective study was conducted on patients with FI who had SNM between 2009 and 2016 at 15 specialized colorectal surgery centers in Latin America. Main outcomes measures were functional outcomes, postoperative complications, requirement of revisional surgery, and requirement of device removal. All patients had failed conservative management and had clinical assessment including recording of the validated Cleveland Clinic Florida Fecal Incontinence Score (CCF-FIS) and, when available, anal manometry and endoanal ultrasound. Patients were followed up for a median of 36.7 (1-84) months.ResultsOne hundred and thirty-one patients [119 females, median age of 62.2 (range 19-87) years] were included. The most common etiology of FI was obstetric injury (n = 60; 45.8%). After successful test lead implantation, the stimulator was permanently placed in 129 patients (98.5%). One patient failed to respond in the test phase and one patient did not proceed to permanent implantation for insurance reasons. Nineteen patients (14.7%) had 19 complications including infection (n = 5, 3.8%), persistent implant site pain (n = 5, 3.8%), generator/lead dislodgment (n = 5, 3.8%), malfunctioning device (n = 3, 2.3%), and hematoma (n = 1, 0.7%). Reimplantation after the first and second stages was necessary in 2 (1.5%) and 3 patients (2.3%), respectively. The device removal rate was 2.2%. At a median follow-up of 36.7 (range 1-84) months, the CCF-FIS significantly improved from a preoperative baseline of 15.9 ± 2.98 to 5.2 ± 3.92 (95%CI: 15.46 vs 4.43; p < 0.0001). Overall, 90% of patients rated their improvement as "significant".ConclusionsSacral nerve stimulation for FI is safe and efficient, even in less wealthy or less developed countries.

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