• Amanda Mandarino Alves, Erika Yuki Yvamoto, Maira Andrade Nacimbem Marzinotto, Ana Cristina de Sá Teixeira, and Flair José Carrilho.
• Faculdade de Medicina da Universidade de São Paulo, Departamento de Gastroenterologia e Hepatologia, São Paulo, SP, Brazil. Electronic address: amanda.malves@hc.fm.usp.br.
• Braz J Infect Dis. 2020 Nov 1; 24 (6): 561-564.

AbstractDuring SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Angiotensin-converting enzyme-2, the functional virus host cell receptor expressed by organs and tissues, seems to have an important role in the pathophysiology and presentation of this disease. In pancreas, this receptor is expressed in both exocrine glands and islets, being a potential target for the virus and subsequent pancreatic injury. There are few articles reporting pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis.Copyright © 2020 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. All rights reserved.

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