• Clinical calcium · May 2007

    Review

    [Disorders of bone and mineral metabolism in CKD: CKD-MBD as a new entity].

    • Yusuke Tsukamoto.
    • Shuwa General Hospital, Division of Nephrology, Japan.
    • Clin Calcium. 2007 May 1; 17 (5): 660-4.

    AbstractSince vascular calcification due to mineral disorder has been revealed a chief cause of decreasing life expectancy of chronic kidney disease (CKD) patients in recent years, the term "renal osteodystrophy" can no longer express the pathophysiology of entire bone and mineral disorder in CKD. This is the reason why new disease entity "CKD-bone mineral disorden (MBD)" was introduced by the GBMI (Global Bone and Mineral Initiative) (one of the workgroups of KDIGO [Kidney Disease Improving Global Outcome]). GBMI has also produced new pathological classification of renal osteodystrophy (ROD) as TMV (turnover, mineralization, volume) classification and LBC (laboratory abnormalities, bone abnormalities, extra osseous calcification) classification for CKD-MBD.

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