• Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim, and Dong-Jin Kim.
• The Joint Replacement Center, Ewha Womans, University School of Medicine, MokDong Hospital, 911-1, MokDong, YangChun-Ku, Seoul, 158-710, Republic of Korea. younghookim@ewha.ac.kr.
• Arch Orthop Trauma Surg. 2015 Oct 1; 135 (10): 1459-67.

PurposeWe studied the outcome in culture-positive and culture-negative infected total knee arthroplasty (TKA).MethodsWe retrospectively reviewed 140 patients with culture-positive and 102 patients with culture-negative infected TKAs. We determined the infection control rate and clinical outcome after repeated debridement, and repeated 2-stage TKA in the culture-positive and culture-negative groups. The mean follow-up was 9.3 years (range 5-14 years) in the culture-positive group and 10.6 years (5-22) in the culture-negative group.ResultsThe overall infection control rate was 56 % in both groups after the first treatment. The overall infection control rate was 90 % in the culture-positive group and 95 % in the culture-negative group. A functional knee was obtained in 90 % in the culture-positive group and 95 % in the culture-negative group.ConclusionsThe data suggest that treatment according to the types of infection in both culture-positive and culture-negative groups after TKA controlled infection and maintained functional TKA with a firm level of fixation for most patients. Repeated debridement and repeated two-stage exchange TKA further improved infection control rates after the initial treatment and increased the likelihood of maintaining a functional TKA.

34 keywords...

hide…