• Internal medicine · Sep 2021

    Case Reports

    Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis.

    • Ayaka Kume, Daisuke Kashiwakuma, Ai Kubodera, Kiyohito Hayashi, Ryo Shimizu, Yoshio Suzuki, and Hiroaki Tanaka.
    • Department of Hematology, Asahi General Hospital, Japan.
    • Intern. Med. 2021 Sep 1; 60 (17): 2853-2858.

    AbstractLymphoproliferative diseases have been associated with various autoimmune diseases. We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage. Because MBL is difficult to diagnose, cases like ours may not be rare. These findings will facilitate our understanding of the mechanism underlying lymphoproliferative diseases and autoimmune diseases.

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