• J. Cardiothorac. Vasc. Anesth. · Jan 2022

    Case Reports

    Factor V Deficiency (Owren's Disease) in a Patient at High Risk for Transfusion-Associated Circulatory Overload and Bleeding During Laser Lead Extraction.

    • Michael G Fitzsimons, Conor Barrett, Scott Streckenbach, and Pavan K Bendapudi.
    • Harvard Medical School, Boston, MA; Division of Cardiac Anesthesia, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA. Electronic address: mfitzsimons@partners.org.
    • J. Cardiothorac. Vasc. Anesth. 2022 Jan 1; 36 (1): 242-245.

    AbstractCongenital factor V deficiency is an extremely rare abnormality and may be associated with significant bleeding as a result of trauma or surgery. Perioperative management primarily includes the administration of fresh frozen plasma to replace the deficient clotting factor. Acute administration of multiple blood products is a risk factor for transfusion-associated circulatory overload. Herein, the case of a 71-year-old man with an ejection fraction of 13% and a history of congenital factor V deficiency who was at risk for significant bleeding and transfusion-associated circulatory overload who underwent successful complex extraction of a right atrial pacing lead is reported.Copyright © 2021 Elsevier Inc. All rights reserved.

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