• Vinayak Bapat, Muhammed Z Khawaja, Rizwan Attia, Ashok Narayana, Karen Wilson, Kirsty Macgillivray, Christopher Young, Jane Hancock, Simon Redwood, and Martyn Thomas.
• Department of Cardiothoracic Surgery, Guy's and St. Thomas' Hospital, London, United Kingdom. vnbapa-t@yahoo.com
• Catheter Cardiovasc Interv. 2012 Apr 1; 79 (5): 733-40.

ObjectivesTo evaluate feasibility and outcome of Transoartic Transcatheter Sapien valve implantation.BackgroundTranscatheter Aortic valve implantation (TAVI) using the Edwards SAPIEN device (Edwards LifeScience, Irvine, CA) is usually performed via the transfemoral (TF) or transapical (TA) routes. Some patients are not suitable for these approaches. We report our experience with the novel transaortic (TAo) approach via a partial upper sternotomy and discuss the advantages and future applications.MethodsBetween January 2008 to March 2011 193 patients with severe aortic stenosis underwent TAVI with the Edwards SAPIEN bioprosthesis at the St. Thomas' Hospital, London. 108 patients were unable to undergo a TF-TAVI and of those 17 were accepted for a TAo-TAVI on the basis of anatomy, risk, LV function, and significant respiratory disease.ResultsThe TAo-TAVI group (n = 17) had more prevalent respiratory disease than the TA-TAVI group (47.0% vs. 18.7%, P = 0.011). Otherwise the groups were similar in demographics and history. Despite this the 30 day mortalities were not significantly different between the groups (TAo-TAVI 4.3% at 30 days versus TA-TAVI 7.7%, P = 0.670). There were no significant differences in procedural complications.ConclusionsThe TA-TAVI approach may not be desirable in patients with severe chest deformity, poor lung function or poor left ventricular function. TAo-TAVI via a partial sternotomy is safe and feasible in these patients.Copyright © 2011 Wiley Periodicals, Inc.

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