• Bradley Y Harris, Matthew F Roth, Bassel G Diebo, Shay Bess, Alexander A Theologis, Justin K Scheer, Frank J Schwab, Virginie Lafage, Christopher P Ames, Richard Hodes, Jennifer Ayamga, Oheneba Boachie-Adjei, and International Spine Study Group.
• Department of Orthopaedic Surgery, NYU Langone Medical Center, New York, NY, USA.
• Spine Deform. 2016 Sep 1; 4 (5): 351-357.

Study DesignRetrospective analysis of propensity score-matched (PSM) observational cohorts.ObjectivesTo evaluate and compare preoperative health-related quality of life (HRQoL) scores and radiographic measurements of young African and US adults with spinal deformity (ASD).Summary Of Background DataYoung ASD patients in the United States are motivated more to correct coronal and sagittal plane deformities than to alleviate pain. Motivations for surgical correction in young ASD patients in Africa have not been previously investigated.MethodsRetrospective review of two large databases of African and US patients with ASD. African patients who underwent ASD surgery were PSM by age, gender, and pelvic tilt with US patients. Preoperative radiographic parameters and HRQoL scores (ODI, SRS-22r, back/leg pain) were compared between cohorts. Pearson correlations used to evaluate relationships between radiographic parameters and HRQoL scores.ResultsFifty-four US patients (average age 22.9 ± 4.9 years; 0% African American) and 54 African patients (24.6 ± 7.2 years) met inclusion criteria. Compared to the United States, African patients had significantly lower body mass index (21.1 ± 3.3 vs. 24.6 ± 7.2) and more severe scoliosis, coronal malalignment, and sagittal malalignment (p < .05). Africans also had significantly better Oswestry Disability Index (12.8 vs. 17.7), worse Scoliosis Research Society questionnaire (SRS-22r)-Appearance (2.5 vs. 3.2), SRS-Function (3.3 vs. 3.9), and SRS-Total (3.2 vs. 3.5) scores than US patients (p < .05). SRS-Appearance scores correlated with Cobb angles of the upper thoracic (r = -0.321), thoracic (r = -0.277), and thoracolumbar (r = -0.300) curves for US patients. For African patients, global sagittal alignment and C7 inclination correlated with SRS-Appearance (r = -0.347, -0.346, respectively).ConclusionsYoung African ASD patients have significantly more severe deformity, less disability, and worse SRS-22r scores preoperatively than a matched cohort of US patients. Spinal deformity and associated poor self-image appear to be the major drivers of surgical intervention in this cohort. Global malalignment in African patients is most closely correlated with appearance scores and should be surgically addressed accordingly.Level Of EvidenceLevel III.Copyright © 2016 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.

16 keywords...

hide…