• Neth J Med · Feb 2019

    Case Reports

    Post-transfusion purpura in a woman with acute myeloid leukemia.

    • E de Kruijff, A J van Gammeren, L Porcelijn, and J W J van Esser.
    • Departments of 1nternal Medicine, Amphia Hospital, Breda, the Netherlands.
    • Neth J Med. 2019 Feb 1; 77 (2): 81-83.

    AbstractPost-transfusion purpura (PTP) is a rare, but severe transfusion reaction in which both donor and autologous platelets are sequestered due to immunization against HPA-1a antigens in HPA-1a negative recipients (HPA: human platelet antigens). We describe a patient who developed PTP during induction therapy for acute myeloid leukaemia. The pitfalls, delays in diagnosing and therapy options of this serious transfusion reaction are discussed.

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