• Hui-Fang Li, Qi-Hong Shen, Xu-Yan Zhou, and Xu Shen.
• Department of Gynecology, Tongxiang Maternal And Child Health Care Hospital, Tongxiang, Zhejiang, China.
• J. Int. Med. Res. 2021 Mar 1; 49 (3): 300060521999568.

ObjectiveThis meta-analysis investigated the analgesic effects of erector spinae plane block (ESPB) in patients undergoing breast surgery.MethodsPubMed, Embase, Web of Science, and the Cochrane Library were searched from database establishment to January 31, 2020. Two reviewers independently extracted the data. The primary outcomes were pain scores and opioid consumption during the first 24 hours after surgery. The risk of bias of the included studies was assessed according to the Cochrane Handbook.ResultsSix randomized controlled trials of 415 patients were included. Compared with the control value, the pain score was significantly lower in the ESPB group at different time points postoperatively. Patients who underwent ESPB required lower opioid consumption (standardized mean difference = -2.02, 95% confidence interval [CI] = -2.85 to -1.20, I2= 91%. The rates of postoperative nausea (risk ratio [RR] = 0.79, 95% CI = 0.48-1.30, I2 = 47%) and postoperative vomiting (RR = 0.76, 95% CI = 0.30-1.96, I2 = 33%) did not differ between the groups. The quality of evidence was low or very low.ConclusionsESPB significantly alleviated pain and reduced opioid consumption after breast surgery. Further research is needed to expand its clinical application.PROSPERO registration number CRD42020167900.

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