• Cell host & microbe · May 2011

    Making space for anti-infective drug discovery.

    • Carl Nathan.
    • Department of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA. cnathan@med.cornell.edu
    • Cell Host Microbe. 2011 May 19; 9 (5): 343-8.

    AbstractThe dwindling supply of effective treatments for infectious disease is cause for alarm. Searches for anti-infectives yielding fewer and fewer novel discoveries have been concentrated in overly restricted regions of target space, screening space, chemical space, and competition space. Appreciating the diverse axes of these spaces may encourage wider exploration.Copyright © 2011 Elsevier Inc. All rights reserved.

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