• Xiaoqian Chen, Weixue Zhu, and Suhua Jiang.
• Department of Pediatrics, First People's Hospital of Foshan, Foshan, Guangdong, PR China.
• Medicine (Baltimore). 2021 Mar 26; 100 (12): e25266e25266.

IntroductionThe objective is to analyze the clinical diagnosis and treatment of children with rescindable posterior encephalopathy syndrome (PRES) and intracranial hemorrhage (ICH) to improve the pediatrician's understanding of PRES combined with ICH in children.Patient Concerns And DiagnosisAfter liver transplantation, the patient developed symptoms of epilepsy and coma. Meanwhile, massive necrosis of acute cerebral infarction and small hemorrhage was observed in the left cerebellar hemisphere and left occipital lobe, respectively. The above symptoms were initially diagnosed as PRES.Interventions And OutcomesAfter adjusting the anti-rejection drug regimen, it was found that the child's neurological symptoms were relieved, and the limb motor function gradually recovered during follow-up. Imaging examination showed significant improvement on abnormal signals in brain.ConclusionIn general, children with PRES may further develop ICH and contribute to a poor prognosis. Early diagnosis, detection of risk factors and timely adjustment of medication regimen are the keys to prevent irreversible brain damage.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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