• Karla Moreno-Tamayo, Betty Manrique-Espinoza, Lyzbeth Beatriz Ortiz-Barrios, Ángel Cárdenas-Bahena, Eliseo Ramírez-García, and Sergio Sánchez-García.
• Unidad de Investigación Epidemiológica y Servicios de Salud. Área Envejecimiento. Instituto Mexicano del Seguro Social. Ciudad de México, Mexico. Electronic address: kmoreno.gdl@gmail.com.
• Maturitas. 2020 Jun 1; 136: 7-12.

ObjectiveTo analyze the influence that sex has on the association between insomnia, sleep quality, sleep duration, and frailty in older adults.Subjects & MethodsCross sectional study from the Cohort Obesity, Sarcopenia, and Frailty in Older Mexican Adults (COSFOMA). In total, 493 older adults aged 64-94 participated. Insomnia was evaluated with the Athens Insomnia Scale and sleep quality with the Pittsburgh Sleep Quality Index. Duration of sleep was classified as short (<5 h and 5-6 hours), recommended (7-8 hours), and long (≥ 9 h). Frailty was operationalized with the Fried phenotype. Furthermore, sociodemographic variables were collected, along with physical and mental health. Logistic regression models were stratified by sex to analyze the relationship between insomnia, sleep quality, sleep duration, and frailty.ResultsParticipants included 299 (60.7 %) women and 194 (39.3 %) men. The average age was 70.1 ± 5.6 years. Frail older adults comprised 13.4 % of the sample (n = 66), while 62.5 %(n = 308) were pre-frail and 24.1 % were not frail (n = 119). In the statistical models adjusted for sociodemographic and health covariates, insomnia, low sleep quality, and sleeping less than five hours were shown to increase the odds of being frail in women, but not in men.ConclusionIn older adult women, the presence of insomnia, low sleep quality, and sleeping less than five hours could promote frailty. Therefore, treatment of sleep problems among women should be prioritized to avoid the onset of this condition.Copyright © 2020 Elsevier B.V. All rights reserved.

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