• J Hand Surg Am · May 2009

    Case Reports

    Necrosis caused by intra-arterial injection of promethazine: case report.

    • Andrew Lee Foret, Andrew P Bozeman, and Waldo E Floyd.
    • Mercer University School of Medicine and OrthoGeorgia, Macon, Georgia 31201, USA. andrewforet@yahoo.com
    • J Hand Surg Am. 2009 May 1; 34 (5): 919-23.

    AbstractPromethazine injections have led to necrosis and gangrene of the distal upper extremity when inadvertently injected into an artery. There have been few case reports of this alarming complication in the literature. We report on 2 cases of intra-arterial promethazine injection that led to amputation.

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