• Internal medicine · Sep 2021

    Case Reports

    A Case of Untreated Squamous Cell Lung Carcinoma May Contribute to the Occurrence of Hemophagocytic Syndrome.

    • Eriko Koda, Hiroki Nishine, Yusuke Saiki, Akihito Tsunoda, Ayano Usuba, Naoki Furuya, and Masamichi Mineshita.
    • Division of Respiratory Disease, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
    • Intern. Med. 2021 Sep 15; 60 (18): 299730022997-3002.

    AbstractA 44-year-old man presented at our hospital to be evaluated for persistent fever and dyspnea. A chest computed tomography (CT) scan showed diffuse ground glass shadows and a left hilar tumor shadow. Upon further examination, he was found to have leukopenia, thrombocytopenia, and elevated lactate dehydrogenase and ferritin levels. He was diagnosed with both squamous cell lung carcinoma by a transbronchial lung biopsy and hemophagocytic syndrome by a bone marrow biopsy. After receiving treatment with dexamethasone and etoposide, the blood test abnormalities and performance status improved. Chemotherapy for lung cancer was initiated. He had a partial response after first-line chemotherapy and thereafter underwent left upper sleeve lobectomy.

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