• J Cutan Med Surg · Sep 2016

    Case Reports

    Flagellate Pattern of Toxic Erythema of Chemotherapy Due to Doxorubicin: A Case Report.

    • Sophie Vadeboncoeur and Benoît Côté.
    • Division of Dermatology, Université de Montréal, Montreal, QC, Canada sophie.vadeboncoeur@umontreal.ca.
    • J Cutan Med Surg. 2016 Sep 1; 20 (5): 481-3.

    BackgroundDoxorubicin is an antineoplastic agent frequently used in diverse cancer regimens. Cutaneous adverse effects have frequently been reported with its use. However, a flagellate-like dermatitis is not mentioned in the literature.ObjectiveThe investigators report a case of toxic erythema of chemotherapy with a flagellate pattern induced by doxorubicin.Methods And ResultsA 75-year-old woman with endometrial cancer received doxorubicin as part of her treatment. After her third cycle, she presented a pruritic vesiculobullous eruption, with linear elements that left hyperpigmented streaks on follow-up. A biopsy was compatible with a drug eruption.ConclusionDoxorubicin is a well-known cause of toxic erythema of chemotherapy. As seen in this patient, the investigators suggest that it also be added to the list of causes of flagellate dermatosis.© The Author(s) 2016.

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