• Courtney Toombs, Baron Lonner, Suken Shah, Amer Samdani, Patrick Cahill, Harry Shufflebarger, Burt Yaszay, Paul Sponseller, and Peter Newton.
• New York University School of Medicine, 550 1st Avenue, New York, NY 10016, USA.
• Spine Deform. 2018 Nov 1; 6 (6): 676-683.

Study DesignPreoperative and two-year follow-up health-related quality of life (HRQOL) data were prospectively collected in 82 Scheuermann kyphosis (SK) and 995 adolescent idiopathic scoliosis (AIS) patients using the Scoliosis Research Society-22 patient questionnaire (SRS-22) outcomes instrument in a multicenter study. Visual analog scale (VAS) scores were also collected for the SK population.ObjectivesThis study assessed changes in HRQOL prospectively and compared them to those occurring in AIS.Summary Of Background DataThere has been limited evaluation of patient-reported HRQOL changes with operative management of SK.MethodsMedian SRS values for the SK and AIS cohorts were compared using a repeated measure of analysis of variance with age as a covariate and using a Mann-Whitney U nonparametric comparison.ResultsKyphosis was corrected from 73.9° to 45.8° (p < .001); the major curve in AIS was corrected from 55.5 to 20.2 (p < .001). Preoperative and magnitude of radiographic correction, kyphosis apex and body mass index in SK were not correlated with baseline or change in HRQOL. SK SRS scores improved after surgery in all domains with the greatest change (2.8-4.4) in self-image (p < .001). Changes in SRS Pain, Activity, and Self-Image domains met the minimal clinically important difference. Baseline SK and AIS scores differed significantly in the Self-Image, Mental Health and Total Score domains, with SK having worse scores (p < .001). At two years postoperatively, the greatest improvements were made in Self-Image, along with Mental Health and Total Score, and the SK group achieved greater gains (p < .001). At two years postoperatively, the SK scores improved to reach equivalent values to the AIS scores. VAS scores improved from 3.69 to 1.51, and these changes were correlated with change in the Pain, Mental Health, and Total Score SRS domains (p < .001).ConclusionsSurgery for SK in the adolescent population results in significant improvements in HRQOL, which outpace those of the AIS population.Level Of EvidenceLevel II.Copyright © 2018 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.

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