• Toshiyuki Sumi, Takumi Ikeda, Takeyuki Sawai, Naoki Shijubou, Kenichi Kure, Yuichi Yamada, Hisashi Nakata, Yuji Mori, and Hiroki Takahashi.
• Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, Japan; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan. Electronic address: tsh715@gmail.com.
• Respir Investig. 2020 Sep 1; 58 (5): 376-380.

BackgroundFor the precise management of advanced lung cancers, bronchoscopy with a high diagnostic yield and abundant tumor specimens are required. In recent years, new devices and techniques have been rapidly developed, including the endobronchial ultrasound (EBUS) using a guide sheath, virtual bronchoscopic navigation (VBN), and ultra-thin bronchoscope (UTB), for the diagnosis of peripheral pulmonary lesions (PPLs). These techniques increase the diagnostic yield for PPL, thus requiring fewer biopsy specimens. VBN is generally not available at the city hospitals in Japan. In this study, using fluoroscopy without VBN, we studied whether the histologic diagnostic yield of radial EBUS for PPLs would be higher using a UTB (without guide sheath) or conventional bronchoscope (CB) (with guide sheath).MethodsWe retrospectively reviewed consecutive patients with suspected lung cancer who underwent bronchoscopy at the Hakodate Goryoukaku Hospital from April 2017 to March 2019. We analyzed 168 patients-102 using UTB and 66 using CB.ResultsThe diagnostic yields for PPL were significantly higher in the UTB group than in the CB group (74.5% vs. 59.1%; P = 0.04). The median examination time was significantly longer in the UTB group than in the CB group (24 vs. 20 min; P = 0.01). There were no statistically significant differences in the complication rate between the UTB and CB groups (3.9% vs. 3.0%; P = 0.69).ConclusionsUTB had a significantly higher tissue diagnostic yield than CB, without the use of VBN.Copyright © 2020. Published by Elsevier B.V.

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