• Ludmila M Mikhaleva, Aleksandr I Mikhalev, Sergey G Shapovaliants, Olesya A Vasyukova, Stanislav A Budzinskiy, Valentina V Pechnikova, Andrey E Birjukov, Konstantin Yu Midiber, and Mikhail Y Sinelnikov.
• Research Institute of Human Morphology, Moscow, Russia.
• Am J Emerg Med. 2021 Oct 1; 48: 374.e5-374.e12.

BackgroundGallstone disease is a burden affecting about 15% percent of the population around the world. The complications of gallstone disease are numerous and many require emergency care. Severe complications are not uncommon and require special attention, as lethal outcome is possible.Case PresentationWe present a retrospective analysis of eight cases describing severe complications of gallstones in patients undergoing endoscopic treatment of chronic gallstones conditions. All patients were admitted to our emergency care department following symptoms onset. The diagnostic difficulties, treatment strategies and outcomes are presented. The associated risk factors and preventative measures are discussed. Two patients developed profuse bleeding, two developed acute pancreatitis, two patients had perforation related complications. One rare case of bilioma and one case of iatrogenic injury are presented. All patients had severe condition, in two cases lethal outcome was a result of co-morbidity and difficulties in management.ConclusionSpecial care should be taken in patients with risk factors of severe complications in order to improve outcome and prevent the development of life-threatening conditions.Copyright © 2021 Elsevier Inc. All rights reserved.

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