• Kevin Chatham-Stephens, Royal Law, Ethel Taylor, Stephanie Kieszak, Paul Melstrom, Rebecca Bunnell, Baoguang Wang, Hannah Day, Benjamin Apelberg, Lee Cantrell, Howell Foster, and Joshua G Schier.
• Division of Environmental Hazards and Health Effects, National Center for Environmental Health, CDC, Atlanta, GA, USA. xdc4@cdc.gov.
• J Med Toxicol. 2016 Dec 1; 12 (4): 350-357.

IntroductionE-cigarette use is increasing, and the long-term impact on public health is unclear. We described the acute adverse health effects from e-cigarette exposures reported to U.S. poison centers.MethodsWe compared monthly counts and demographic, exposure, and health effects data of calls about e-cigarettes and conventional cigarettes made to poison centers from September 2010 through December 2014.ResultsMonthly e-cigarette calls increased from 1 in September 2010, peaked at 401 in April 2014, and declined to 295 in December 2014. Monthly conventional cigarette calls during the same period ranged from 302 to 514. E-cigarette calls were more likely than conventional cigarette calls to report adverse health effects, including vomiting, eye irritation, and nausea. Five e-cigarette calls reported major health effects, such as respiratory failure, and there were two deaths associated with e-cigarette calls.ConclusionE-cigarette calls to U.S. poison centers increased over the study period, and were more likely than conventional cigarettes to report adverse health effects. It is important for health care providers and the public to be aware of potential acute health effects from e-cigarettes. Developing strategies to monitor and prevent poisonings from these novel devices is critical.

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