• Li-Juan Huang, Liang-Yan Shi, and Jie Duan.
• Medical School, Wuhan University of Science and Technology.
• Medicine (Baltimore). 2021 Apr 2; 100 (13): e24922e24922.

RationalOvarian sertoli-leydig cell tumor (OSLCT) is extremely rare. We reported a OSLCT case in whom postmenopausal vaginal bleeding was the first symptom.Patient ConcernsThe patient came to our hospital due to postmenopausal vaginal bleeding.DiagnosesSerum tumor markers and color Doppler ultrasound for her pelvic cavity were negative. The patient was finally diagnosed with left OSLCT by pathology. It was difficult to make a definite diagnosis before operation, the diagnosis of OSLCT required postoperative pathology in the patients.Interventionsthe patient underwent laparoscopic hysterectomy+bilateral adnexectomy+lysis of pelvic adhesions.OutcomesPostoperative laboratory examinations were normal. The patient was discharged from our hospital on the seventh day after operation and came to our hospital for follow-up check in April 2020. Physical and laboratory examinations were normal.LessonsOSLCT can show different endocrine abnormalities, which are related to the various types of tumor tissues. Missed diagnosis and misdiagnosis are likely to occur in the patients who only have elevated serum testosterone. For the menopausal women with elevated serum testosterone, ovarian tumor shoule be highly suspected after excluding adrenal gland-related diseases.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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