• Gang Huang, Juan Yan, Jiahua Zou, Chuxiang Hu, Dongbei Huang, Qiang Huang, Peize Chen, Feiyan Zhang, and Liping Gong.
• Affifiliated Hospital of Jiangxi University of Traditional Chinese Medicine.
• Medicine (Baltimore). 2021 Apr 2; 100 (13): e25312e25312.

BackgroundPlaque psoriasis (PSO) is a common clinical chronic inflammatory skin disease. The incidence rate is increasing year by year due to the fast pace of work and unhealthy diet. Fire needle has been widely used in the treatment of PSO. However, the efficacy of fire needle for PSO is uncertain. Thus, the purpose of this systematic review is to evaluate the effectiveness and safety of fire needle for PSO (blood stasis syndrome).MethodsThe following electronic databases will be searched from inception to October 2020:PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure, WangFang Database, Chinese Science Journal Database, Chinese Biomedical Literature Database. In addition, other documents that meet the requirements will be manually searched, including conference papers, dissertations, etc. All randomized controlled trials using fire needle to treat PSO (blood stasis syndrome) that meet the criteria for inclusion will be included. The primary outcomes are clinical efficacy, Psoriasis area and severity index. Secondary outcomes include Itchy, TCM evaluation standard syndrome score, Dermatological quality of life index, and adverse events. To complete data synthesis and assess the risk of bias, we will use the RevMan V.5.3 software.ResultsThe review results will be published in a peer-reviewed journal.ConclusionThis study will provide high-quality evidence based medicine to evaluate the effectiveness and safety of fire needle for PSO (blood stasis syndrome), and further seek its scientific and effective chinese medicine treatment methods.Inplasy Registration NumberINPLASY202120007.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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