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Case Reports
Congenital adrenal hyperplasia with testicular tumors, aggression, and gonadal failure.
- E J Keely, I Matwijiw, J A Thliveris, and C Faiman.
- Department of Medicine, University of Manitoba, Winnipeg, Canada.
- Urology. 1993 Apr 1; 41 (4): 346-9.
AbstractBilateral testicular tumors (adrenal rests) may occur in untreated or poorly controlled congenital adrenal hyperplasia. This case report describes two unique associated phenomena: (1) psychologic disturbances similar to those seen with exogenous androgen abuse, which resolved with appropriate glucocorticoid suppression of androgen over-production by this abnormal adrenal/adrenal rest tissue; and (2) testicular failure which showed a partial, delayed recovery with corticosteroid therapy. The need for a careful history and biochemical screening for all patients with bilateral testicular tumors is reinforced.
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