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Case Reports
Can anisodamine be a potential substitute for high-dose atropine in cases of organophosphate poisoning?
- W Wang, Q-F Chen, H-L Ruan, K Chen, B Chen, and J-M Wen.
- Department of Emergency, the First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.
- Hum Exp Toxicol. 2014 Nov 1; 33 (11): 1186-90.
AbstractA case of organophosphate (OP) poisoning was admitted to the emergency room. The patient accepted treatment with pralidoxime (PAM), atropine, and supporting therapy. It was observed that even after 22 h after treatment, 960 mg of atropine was not enough for the patient to be atropinized. However, a 160-mg follow-up treatment of anisodamine was quite enough for atropinization after 4 h. As a case report, more studies are required before any definite conclusion can be reached regarding the use of anisodamine as a potential substitute for high-dose atropine in cases of OP poisoning.© The Author(s) 2014.
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