• Stuart A Taylor, Andrew Slater, Steve Halligan, Lesley Honeyfield, Mary E Roddie, Jamshid Demeshski, Hamdam Amin, and David Burling.
• Department of Imaging, University College Hospital, 2F Podium, 235 Euston Rd, London NW1 2BU, England. csytaylor@yahoo.co.uk
• Radiology. 2007 Jan 1; 242 (1): 120-8.

PurposeTo prospectively investigate the relative accuracy and reproducibility of manual and automated computer software measurements by using polyps of known size in a human colectomy specimen.Materials And MethodsInstitutional review board approval was obtained for the study; written consent for use of the surgical specimen was obtained. A colectomy specimen containing 27 polyps from a 16-year-old male patient with familial adenomatous polyposis was insufflated, submerged in a container with solution, and scanned at four-section multi-detector row computed tomography (CT). A histopathologist measured the maximum dimension of all polyps in the opened specimen. Digital photographs and line drawings were produced to aid CT-histologic measurement correlation. A novice (radiographic technician) and an experienced (radiologist) observer independently estimated polyp diameter with three methods: manual two-dimensional (2D) and manual three-dimensional (3D) measurement with software calipers and automated measurement with software (automatic). Data were analyzed with paired t tests and Bland-Altman limits of agreement.ResultsSeven polyps (ConclusionFor polyps smaller than 1 cm, measurement differences of up to 2.5 mm are within the expected limits of inter- and intraobserver agreement for all measurement techniques. Automated and manual 3D polyp measurements are more accurate than manual 2D measurements.Copyright (c) RSNA, 2006.

25 keywords...

hide…