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- L H Edmunds.
- Division of Cardiothoracic Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
- Ann. Thorac. Surg. 1998 Nov 1; 66 (5 Suppl): S12-6; discussion S25-8.
AbstractThis article reviews the roles of the contact and complement systems and of neutrophils and monocytes in the inflammatory response to cardiopulmonary bypass and open heart operation. These blood proteins and cells, together with other blood elements, produce the vasoactive and cytotoxic substances and microemboli that cause the morbidity associated with cardiopulmonary bypass and open heart operation.
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