• S Ryan Greysen, Andrew D Auerbach, Matthew D Mitchell, Jennifer N Goldstein, Rachel Weiss, Armond Esmaili, Ifedayo Kuye, Efren Manjarrez, Maralyssa Bann, Jeffrey L Schnipper, and HOMERuN collaborative working group.
• Penn Medicine Center for Evidence-based Practice, Section of Hospital Medicine, Division of General Internal Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Ryan.Greysen@pennmedicine.upenn.edu.
• J Gen Intern Med. 2021 Jun 1; 36 (6): 171517211715-1721.

BackgroundThere are currently no evidence-based guidelines that provide standardized criteria for the discharge of COVID-19 patients from the hospital.ObjectiveTo address this gap in practice guidance, we reviewed published guidance and collected discharge protocols and procedures to identify and synthesize common practices.DesignRapid review of existing guidance from US and non-US public health organizations and professional societies and qualitative review using content analysis of discharge documents collected from a national sample of US academic medical centers with follow-up survey of hospital leaders SETTING AND PARTICIPANTS: We reviewed 65 websites for major professional societies and public health organizations and collected documents from 22 Academic Medical Centers (AMCs) in the US participating in the HOspital MEdicine Reengineering Network (HOMERuN).ResultsWe synthesized data regarding common practices around 5 major domains: (1) isolation and transmission mitigation; (2) criteria for discharge to non-home settings including skilled nursing, assisted living, or homeless; (3) clinical criteria for discharge including oxygenation levels, fever, and symptom improvement; (4) social support and ability to perform activities of daily living; (5) post-discharge instructions, monitoring, and follow-up.LimitationsWe used streamlined methods for rapid review of published guidance and collected discharge documents only in a focused sample of US academic medical centers.ConclusionAMCs studied showed strong consensus on discharge practices for COVID-19 patients related to post-discharge isolation and transmission mitigation for home and non-home settings. There was high concordance among AMCs that discharge practices should address COVID-19-specific factors in clinical, functional, and post-discharge monitoring domains although definitions and details varied.

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