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Comparative Study
Increased risk of lead fracture and migration in dystonia compared with other movement disorders following deep brain stimulation.
- J Yianni, D Nandi, A Shad, P Bain, Ralph Gregory, and Tipu Aziz.
- The Oxford Movement Disorder Group, Department of Neurological Surgery, The Radcliffe Infirmary, Oxford OX2 6HE, UK.
- J Clin Neurosci. 2004 Apr 1; 11 (3): 243-5.
AbstractDeep brain stimulation (DBS) therapy is a continually expanding field in the functional neurosurgical treatment of movement disorders. However, the occurrence of adverse events related to implanted hardware cannot be overlooked. We report on a specific feature noted in our experience of DBS-related complications. From 1998 until present we have found an overall rate of 5.3% of DBS electrode lead dysfunction (out of 133 patients) in our series (slipped leads 2.3%, lead fracture 3.8%). Interestingly, all of these failures occurred in dystonia patients (18.4% of all dystonia patients and 9.2% of all electrodes). We postulate on mechanisms that may explain why these complications predominate in this group of patients.
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