• Adam Ogna, Helene Prigent, Line Falaize, Karl Leroux, Dante Santos, Isabelle Vaugier, David Orlikowski, and Frederic Lofaso.
• Hôpital Raymond Poincaré, Service de Réanimation médicale et unité de ventilation à domicile, AP-HP, Garches, 92380, France.
• Clin Respir J. 2018 Mar 1; 12 (3): 890-894.

IntroductionMouthpiece ventilation represents a valuable treatment for patients needing daytime non-invasive ventilation. This modality is however underused, in part because of limitations in the available equipment.ObjectiveTo develop a new flexible and moldable mouthpiece, aiming to address some of the issues of the currently available interfaces.MethodsWe compared two commercially available and the newly developed mouthpieces in a bench test using four life-support home ventilators and three settings per ventilator.ResultsThe three interfaces showed marked differences in their resistive characteristics. In the volume-controlled setting (VC-CMV) with 500 mL tidal volume (VT ), the delivered VT , ranged between 459 ± 7 mL (-8%) and 501 ± 4 mL (+0.2%), according to the used ventilator. In the VC-CMV setting with VT 1000 mL, one of the ventilators did not assure the set VT with the new mouthpiece, because of the high-pressure limitation. In the pressure-controlled setting (PC-CMV at 20 cmH2 O), the effective pressure differed between the tested interfaces according to their resistance, resulting in a decrease in the delivered VT .ConclusionsThey found measurable differences in the ventilation's performances comparing the interfaces for mouthpiece ventilation, which seem to have a minor clinical relevance in the most settings, but should be systematically checked. They validated in-vitro the newly developed mouthpiece with respect to the ventilation performances; a clinical study is needed to investigate the potential advantages we expect from the new mouthpiece.© 2016 John Wiley & Sons Ltd.

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