• Internal medicine · Sep 2021

    Case Reports

    Three Cases of Esophageal Cancer Related to Fanconi Anemia.

    • Mia Fujisawa, Masashi Matsushima, Takashi Ueda, Motoki Kaneko, Ryutaro Fujimoto, Masaya Sano, Erika Teramura, Makiko Monma, Hajime Mizukami, Fumio Nakahara, Hidekazu Suzuki, Takayoshi Suzuki, Miharu Yabe, and Toshimasa Yabe.
    • Divisions of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University, School of Medicine, Japan.
    • Intern. Med. 2021 Sep 15; 60 (18): 2953-2959.

    AbstractThe risk of carcinogenesis increases after 20 years old in patients with Fanconi anemia (FA). We herein report three rare cases of FA combined with esophageal cancer in women; all patients were diagnosed with FA in early childhood. Patients 1 and 2 were diagnosed with advanced and superficial esophageal cancer, respectively, at 21 and 30 years old, respectively. Patient 3 was diagnosed with superficial esophageal cancer, underwent curative surgery at 26 years old, and survived for over 5 years without recurrence. Therefore, establishing a protocol for the early detection of esophageal cancer in FA patients over 20 years old is important.

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