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Randomized Controlled Trial Clinical Trial
Modification by fentanyl and alfentanil of the intraocular pressure response to suxamethonium and tracheal intubation.
- J Sweeney, S Underhill, T Dowd, and S M Mostafa.
- Royal Liverpool Hospital.
- Br J Anaesth. 1989 Dec 1; 63 (6): 688-91.
AbstractWe have measured in a double-blind study the changes in intraocular pressure (IOP) in 40 consecutive patients (pretreated with fentanyl or alfentanil) who received suxamethonium and tracheal intubation. Although IOP increased significantly following administration of suxamethonium, mean IOP in both groups remained significantly less than control values (P less than 0.002). Tracheal intubation caused a further significant increase in IOP in the fentanyl, but not the alfentanil group. There were no significant differences in mean IOP between the fentanyl and alfentanil groups. Both opioids reduced, but did not abolish the haemodynamic responses to tracheal intubation.
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