• Yue Zhou, Xiao Yan, Fengjun Ma, Qingchang Xia, Yunping Lu, Wenyuan Li, Shuai Song, Yan Sun, Yuxia Ma, and Yuning Ma.
• Shandong University of Traditional Chinese Medicine.
• Medicine (Baltimore). 2021 Apr 9; 100 (14): e25389e25389.

BackgroundCoronavirus disease 2019 (COVID-19) is still spreading around the world. Moxibustion, as a significant therapy in traditional Chinese medicine (TCM), has been widely used to treat COVID-19, especially in recovery period. The study will aim to assess the efficacy and safety of moxibustion for COVID-19 convalescence.MethodsWe will systematically search the relevant randomized controlled trials in the 7 databases from inception to February 2021, including PubMed, MEDLINE, Embase, Cochrane Clinical Trials Database, Web of Science, China National Knowledge Infrastructure and Chinese Biomedical Literature Database. No language and publication status restrictions will be applied. Two reviewers will independently conduct and screen all included studies and the meta-analysis will be performed with RevMan V5.3 (The Cochrane Collaboration, Oxford, England).ResultsThe study will provide a high-quality convincing assessment of the efficacy and safety of moxibustion for the treatment of COVID-19 convalescence, which will be published in a peer-reviewed journal.ConclusionOur study will give more comprehensive evidence of the effectiveness of moxibustion for COVID-19 convalescence.Trial Registration NumberCRD42021230364.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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