• Pei-Chen Chen, Chiu-Hsuan Cheng, and Dah-Ching Ding.
• Department of Obstetrics and Gynecology.
• Medicine (Baltimore). 2021 Apr 9; 100 (14): e25460e25460.

RationaleWe report a case with inguinal subcutaneous endometriosis without typical cyclic dysmenorrhea and accompanied with a hernia sac treated with resection of the tumor and herniorrhaphy.Patient ConcernsA 40-year-old woman had a painless enlarged inguinal nodule for 3 months.DiagnosesSubcutaneous endometriosis accompanied with a hernia sac.InterventionsUltrasonography showed a hypoechoic lesion (3.0 cm × 2.0 cm), and an inguinal subcutaneous tumor was first suspected. After surgical exploration, a cystic lesion was excised and the hernia hole was repaired by herniorrhaphy. The immunohistochemical analysis of the small endometriotic cyst-like lesion revealed calretinin (-) in epithelial cells and CD10 (+) in stromal cells, indicative of subcutaneous endometriosis accompanied with a hernia sac.OutcomesThe patient was followed up for 1 year and without recurrence.LessonsCutaneous endometriosis accompanied with a hernia sac can be presented without typical endometriosis-associated symptoms such as dysmenorrhea. Inguinal endometriosis might be the differential diagnosis of inguinal painless nodules.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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