• Yao Pan, Lu Chen, Dan Shi, Ying Chen, and Ri-Sheng Yu.
• Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Jiefang Road 88#, Hangzhou 310009.
• Medicine (Baltimore). 2021 Apr 9; 100 (14): e25471e25471.

RationaleMyopericytoma of the parotid gland is a rare condition of which preoperative definitive diagnosis is relatively challenging. The purpose of this case report is to highlight the radiologic features of myopericytoma of parotid gland.Patient ConcernsA 62-year-old man presented with a history of a walnut-size mass in left parotid gland when yawned for half-month, and a 48-year-old woman complaint about a grape-size, painless mass behind the right ear for a month.DiagnosesRadiological examinations suggested that both lesions were cyst-solid mixed lesions with relatively smoothed margins, with or without significant enhancement while the lesion without enhancement had a hemorrhage. Then a diagnosis of benign tumor arising from the parotid gland was made. Final diagnosis of myopericytoma was confirmed by histopathological and immunohistochemical examinations after surgical resection.InterventionsBoth patients underwent excision of the tumor and the superficial parotidectomy with facial nerve preservation.OutcomesBoth patients recovered without any intraoperative or postoperative complication and had no signs of recurrence during a 17-month and 5-year follow-up.LessonsParotid gland myopericytoma is an exceedingly rare tumor which diagnosis can be challenging, and this is the first published report specifying the magnetic resonance features of the disease.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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